产品货号：
GS4707
中文名称：
重组大鼠IL-7
英文名称：
Recombinant Rat Interleukin-7
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 14.9kDa,a single non-glycosylated polypeptide chain containing 129 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-7(IL-7)is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus.It binds to the IL-7 receptor,a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain.IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells,T cells and NK cells.Furthermore,IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.Rat IL-7 contains 129 amino acid residues and has three disulfide bonds.In addition,it has approximately 57%and 88%amino acid sequence identity with human and murine IL-7.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组大鼠IL-7，IL-7, Rat，Recombinant Rat Interleukin-7
储存条件：冷冻（-20℃）
概述
Interleukin-7(IL-7)is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus.It binds to the IL-7 receptor,a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain.IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells,T cells and NK cells.Furthermore,IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.Rat IL-7 contains 129 amino acid residues and has three disulfide bonds.In addition,it has approximately 57%and 88%amino acid sequence identity with human and murine IL-7.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 2.0ng/ml,corresponding to a specific activity of>5.0×105 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rRtIL-7 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | DCHIKDKDGK AFGSVLMISI NQLDKMTGTD SDCPNNEPNF FKKHLCDDTK EAAFLNRAAR KLRQFLKMNI SEEFNDHLLR VSDGTQTLVN CTSKEEKTIK EQKKNDPCFL KRLLREIKTC WNKILKGSI |
相关搜索：重组大鼠IL-7，IL-7, Rat，Recombinant Rat Interleukin-7